We should not purposely put ourselves in danger. The Lord Jesus is our example:
And Jesus answering said unto him, It is said, Thou shalt not tempt the Lord thy God.
Luke 4:12
An example of how to practice Mark 16:17-18 and Luke 10:19 can be found in Acts 28:1-6 where Paul unintentionally encounters a viper and he is miraculously protected from harm.